Thursday, January 15, 2026

Signos and the Case for Seeing Your Metabolism in Actual Time

What if the largest breakthrough in weight administration shouldn’t be a brand new weight loss plan, however lastly seeing how your physique responds in actual time?

That query sat on the middle of my dialog with Sharam Fouladgar-Mercer, CEO and co-founder of Signos, a steady glucose monitoring (CGM) and AI-powered well being platform constructed to assist folks handle weight by understanding their metabolism. January is when motivation is excessive and the wellness noise is loud, however additionally it is when lots of people notice how laborious it’s to stay with generic recommendation that doesn’t match actual life. This episode is about why personalization issues, how metabolic indicators can change the best way you consider meals and train, and what occurs when well being expertise shifts from reporting the previous to guiding the following choice.

Sharam defined how Signos pairs a CGM with an AI-driven expertise that turns glucose knowledge into sensible actions. The purpose is to not drive folks into inflexible guidelines or excessive restrictions. As a substitute, it’s about studying how your physique reacts to on a regular basis selections, then utilizing that suggestions to cut back spikes, enhance consistency, and construct habits you may really reside with. We talked about easy interventions, like altering the order of meals in a meal, timing motion extra intelligently, and recognizing patterns that might in any other case keep invisible.

Two private tales introduced the dialog to life. Sharam shared how he misplaced 25 kilos whereas rising his calorie consumption, which challenges lots of assumptions folks carry into weight reduction. He additionally shared a narrative from his household life, the place his spouse’s deep sleep elevated from roughly 20 minutes an evening to round 60 minutes after specializing in glucose stability, even whereas whole sleep time remained restricted through the intense interval of elevating younger children. It’s the type of element that hits dwelling for anybody who has ever tried to make more healthy selections whereas exhausted and stretched skinny.

We additionally explored why FDA clearance issues for Signos and what that might imply for mainstream entry. Over-the-counter availability reduces friction, can decrease price, and opens the door to broader adoption, together with potential FSA and HSA eligibility. Trying forward, Sharam shared a imaginative and prescient that goes past weight administration, connecting metabolic well being to the lengthy arc of prevention and continual situations the place insulin resistance performs a task.

When you’ve got ever felt like you might be doing all of the “proper” issues and nonetheless not seeing outcomes, this episode will make you rethink what “proper” even means. And in case you might lastly see your metabolism in actual time, would it not change the way you method meals, sleep, train, and the habits you wish to maintain this 12 months?

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